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Russell V. Anthony, PhD

Hill Professor
Colorado State University
Fort Collins, Colorado

Dr. Russ Anthony holds the Hill Professorship within the Department of Biomedical Sciences, College of Veterinary Medicine, Colorado State University. Russ grew up on a diverse farm & ranch operation in central Nebraska, which he and his brother still manage. Dr. Anthony received his B.S. at Kansas State University in 1977, his M.S. at the University of Nebraska in 1979 and a Ph.D. from the University of Wyoming in 1983. He was a postdoctoral fellow at the University of Florida, Department of Biochemistry during 1984 and 1985, before joining the faculty at the University of Missouri in January 1986. While at the University of Missouri, Dr. Anthony’s primary appointment was in Animal Sciences, with a joint appointment in Biochemistry. Beginning in January, 1994, Dr. Anthony moved his research program to Colorado State University, and soon thereafter began collaborations with faculty in the Department of Pediatrics at the University of Colorado, where he accepted a joint appointment in 1998. Dr. Anthony’s research continues to focus on maternal-placental-fetal interactions in both normal and compromised pregnancies. The pregnant sheep has been his “animal model of choice,” since the ability to place indwelling catheters on both the maternal and fetal sides of the placenta in sheep has allowed Dr. Anthony and colleagues to assess the nutrient/hormone/waste uptake, transfer and utilization, under steady-state non-stressed, non-anesthetized conditions. More recently his laboratory developed the use of lentiviral vectors to deliver and express short hairpin-RNA specifically within trophoblast cells in vivo. This approach allows the specific targeting of gene expression solely within the trophoblast lineages within the placenta. By utilizing in vivo RNA interference within the sheep placenta, Dr. Anthony’s laboratory is now examining the in vivo physiological ramifications of altering the expression of specific genes within the placenta.

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